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Ultra Probioplex™ Duo 30 Probiotic Capsules

Ultra Probioplex™ Duo 30 Probiotic Capsules

Designed to support normal bowel movements and suited to those travelling or taking antibiotics; Ultra Probioplex™ Duo contains 4 different strains of live bacteria alongside Saccharomyces boulardii, blackberry extract and vitamin D.

Key Features

    • A blend of 8.5 billion live bacteria and 6 billion Saccharomyces boulardii (a non-pathogenic yeast)
    • Guaranteed number of live bacteria until expiry date
    • No need to refrigerate; Ultra Probioplex™ Duo features ProtectAir technology so is stable at room temperature
    • Added blackberry fruit and leaf extract and vitamin D

Why choose Ultra Probioplex™ Duo?

Ultra Probioplex™ Duo is a unique duo combination of Saccharomyces boulardii and live bacteria that has superior stability and is ideal for those travelling or taking antibiotics.

This formula contains 8.5 billion extensively researched live bacteria strains and 6 billion Saccharomyces boulardii. The bacterial strains are L. acidophilus NCFM®, L. paracasei Lpc-37, B. lactis Bi-07® and Bi-04.

Ultra Probioplex™ Duo also contains vitamin D which contributes to the normal function of the immune system.

This formula features ProtectAir technology which guarantees the number of live bacteria and their quality without refrigeration until the expiry date.

Products containing live bacteria can vary hugely in strength, efficacy and safety with inferior products falling short for a number of reasons. At Nutri Advanced, we make sure that our products are manufactured to the highest possible standards to ensure that it reaches you in tip top condition. Our extensive range of products contain varying strains and quantities of live bacteria so there is one to suit every individual.

Which strains are included?

Ultra Probioplex™ Duo contains 4 strains of well-studied live bacteria: Lactobacillus acidophilus NCFM®, Lactobacillus paracasei Lpc-37, Bifidobacterium lactis Bi-04, Bifidobacterium lactis Bi-07®.

The NCFM® strain of Lactobacillus acidophilus is an extensively tested and effective acidophilus strain.

Bifidobacterium lactis Bi-07® is an abundant type of bacteria in humans.

Saccharomyces boulardii is a unique, safe, non-pathogenic yeast that is antibiotic resistant.

The combination of the 4 strains of live bacteria used in Ultra Probioplex Duo have previously been demonstrated in a double-blind, placebo-controlled study to help restore the levels of good bacteria in the gut following antibiotic use.

The addition of Saccharomyces boulardii means this product is suitable for use both during and after antibiotic therapy.

Engelbrekston et al. Probiotics to minimize the disruption of faecal microbiota in healthy subjects undergoing antibiotic therapy. Journal of Medical Microbiology. May 2009, Volume 58, p 663-670

What is ProtectAir™?

ProtectAir™ is a triple action moisture defence system that protects the live probiotic bacteria so they can stay alive and at full strength at room temperature (30°C)

 • 75% less moisture from the capsule itself

 • 50% less moisture from the air inside the bottle.

 • 75% less moisture activity in the probiotic

Who should take Ultra Probioplex™ Duo?

Ideal support whilst travelling or on holiday.

Not suitable for patients with a central venous catheter, critically ill patients or for patients with weakened immune function.

Is this product suitable for children?

Yes, this product can be taken from 3 years but the capsule may need to be split and opened for younger children.

Recommended dosage for children:
3 to 12 years: 1 capsule daily

Read more about digestion, probiotics & gut health on our dedicated page here: Don't Be a Misery Guts!

Product code: 44066

  • Features

    Ultra Probioplex Duo is an exciting new formula providing not only 4 strains of live bacteria, but also Saccharomyces boulardii, as well as blackberry extract and vitamin D. This is a super stable formula that does not need to be refrigerated, making it perfect for “on the go” and when travelling.


    The 4 strains of well-studied live bacteria include L. acidophilus NCFM®, L. paracasei Lpc-37, B. lactis Bi-07® and Bi-04. Each capsule provides 8.5 billion of these live organisms.


    A combination of these strains has been shown in studies to reduce the incidence, duration and severity of antibiotic-associated diarrhoea. It is suitable for those taking antibiotics and may be helpful to replenish intestinal flora following antibiotic use or diagnostic stool testing.


    Ultra Probioplex™ Duo may help support normal bowel movements and has broad gastrointestinal and immune system support functions.


    Each capsule of Ultra Probioplex™ Duo contains 6 billion Saccharomyces boulardii. S. boulardii is a non-pathogenic yeast strain isolated from the skins of tropical fruits.


    Saccharomyces boulardii has been significantly researched, and its anti-bacterial effects have been well studied, indicating that several mechanisms are used to protect against pathogenic bacteria, as well as acting directly on pathogenic organisms. Human clinical studies have found S. boulardii to be effective for the management of gastrointestinal bacterial infection in both children and adults.


    The majority of evidence shows that Saccharomyces boulardii orally can help prevent antibiotic-associated diarrhoea in both adults and children.


    The efficacy of S. boulardii for preventing traveller’s diarrhoea has been demonstrated in a large cohort of travellers, where it has been shown to significantly reduce the incidence of diarrhoea in a dose-dependent manner.


    Research has shown that taking Saccharomyces boulardii orally in combination with vancomycin or metronidazole, reduces the reoccurrence of Clostridium difficile diarrhoea in adults and children. And there is evidence to suggest it may protect against infection relapse.


    Studies have collectively suggested the beneficial effect of S. boulardii in inflammatory bowel disease, although more research is needed.


    Research has shown that blackberries (Rubus fructicosus L.) help to feed friendly bacteria and support a diverse and balanced gut microbial environment. Blackberries not only provide health-promoting compounds including anthocyanins and ellagitannins but can also act as a prebiotic to promote the growth of beneficial bacteria such as Bifidobacteria and Lactobacillus.


    Blackberries have a long traditional history in soothing the gut and providing comfort. They contain anthocyanins, which studies have shown, are further broken down in the gut into smaller compounds which have been shown to have anti-inflammatory activity, which may help to soothe a struggling gut.


    Research has also found that blackberry juice has anti-microbial effects against food-borne pathogens including Listeria, Salmonella and E. coli. The results showed that blackberry juice significantly inhibited the growth of these unwanted pathogens, and yet stimulated the growth of friendly bacteria. 


    Ultra Probioplex™ Duo also contains vitamin D, which contributes to the normal function of the immune system.


    The ID Guarantee: The purity, clinical reliability, and predicted safety of Metagenics™ probiotic formulas are guaranteed through the scientific certification of strains with established health benefits. Assuring potency and high viability, each strain is also tested for acid tolerance and cell adherence in vitro.


    Only 1-2 capsules per day are needed. Suitable for vegetarians and those who are dairy -free.

  • Ingredients

    Each capsule typically contains       % NRV* 
    Blend of live bacteria:   8.5 billion live organisms*    ✝
       Lactobacillus acidophilus NCFM®        ✝
       Lactobacillus paracasei Lpc-37        ✝
       Bifidobacterium lactis Bi-04        ✝
       Bifidobacterium lactis Bi-07®        ✝
       Saccharomyces boulardii   6 billion live organisms    ✝
    Blackberry fruit and leaf extract
    (Rubus fructicosus L.)
      50 mg
    Vitamin D (cholecalciferol) (50iu)   1.25 μg    25

    *The exclusive ProtectAir production technology was specially developed by Metagenics. It guarantees the number of live bacteria and their quality until the end of the best-before date when stored at room temperature.
    * NRV is the Nutrient Reference Value
    ✝ NRV not yet established

    Other ingredients:
    Capsule: Hydroxypropyl methylcellulose
    Microcrystalline cellulose
    Magnesium stearate
    Silicon dioxide

    This product is hypoallergenic / does not contain any of the 14 major allergens listed in Annex II (1169/2011) of the EU Food Information for Consumers Regulation.

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